Lab helps to identify the tropism of roseolovirus (Links to an external site)
The Bigley lab, in collaboration with Michael Paley’s lab, identify the tropism of roseolovirus in the thymus and the resultant molecular dysregulation. Transcriptomic profiling of thymic dysregulation and viral tropism after neonatal roseolovirus infection June 4, 2024 Belean A, Xue E, Cisneros B, Roberson EDO, Paley MA, Bigley TM. Transcriptomic profiling of thymic dysregulation and […]
Bigley honored with 2024 ASCI Young Physician-Scientist Award (Links to an external site)
The honor recognizes 52 physician-scientists nationwide who are early in their careers and have had notable achievements in their research. The annual award will be presented in April in Chicago at the joint annual meeting of ASCI, the Association of American Physicians and the American Physician Scientists Association.
Collaboration characterizes the molelucar mechanism of C-terminal COPA variants (Links to an external site)
The Bigley lab collaborates with Selket Delagontaine in the Meyts lab to show how C-terminal domain variant in COPA result in autoinflammation due to increased ER stress.
Bigley lab publishes phenotype expansion of IKAROS GOF (Links to an external site)
This characterization of a rare inborn error of immunity demonstrates a phenotypic expansion to include necrobiotic xanthogranuloma.
Bigley presents at Sugar Science’s Ask The Expert (Links to an external site)
Tarin Bigley presented research on the role of murine roseolovirus in autoimmunity along with development of anti-insulin antibodies and insulitis for Sugar Science’s Ask The Expert event.